ROLE OF THE COMBINATION OF CYCLIN-DEPENDENT KINASE INHIBITORS (CDKI) AND RADIOTHERAPY (RT) IN THE TREATMENT OF METASTATIC BREAST CANCER (MBC): ADVANTAGES AND RISKS IN CLINICAL PRACTICE

Targeting cell cycle has become the gold standard for metastatic breast cancer (MBC), being cyclin-dependent kinase inhibitors (CDKIs) cornerstones of its treatment, alongside radiotherapy (RT).To date, no definite evidence regarding safety and efficacy of the combination of CDKIs plus radiotherapy (RT) is currently available.Purpose of Optical Dri

Abstract Background Over the last decades numerous initiatives have been set up that aim at translating the best available medical knowledge and treatment into clinical practice.The inherent complexity Magetic play of the programs and discrepancies in the terminology used make it difficult to appreciate each of them distinctly and compare their spe

Abstract White lupin (Lupinus albus L.) is an ancient grain legume that is still undergoing improvement of domestication traits, including vernalization-responsiveness, providing frost tolerance and preventing winter flowering in autumn-sowing agriculture, Baby Bottle Nipples and vernalization-independence, conferring drought escape by rapid flower

The tidal river network area of the Pearl River Delta uses the ebb-and-flow differences between tidal level of the outer river and water level of the inland river to divert clear water for regulation.This is an effective way to improve the water environment of the tidal river TIG Gloves network.The central ditch of Hengqin New District is in the ti